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Current treatments for neurological disorders include hormone replacement therapy and antioxidants, which primarily slow disease progression, lack the ability to reverse the disease, and have limited efficacy

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A July 2024 Harvard study found diabetes patients prescribed semaglutide were over four times likely to develop NAION, while those prescribed it for weight loss were over seven times likely to develop this condition

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GLP-1 released in the gut has a half-life of just minutes in the bloodstream, whereas semaglutide and tirzepatide have half-lives measured in days