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Body weights were matched to the SEMA-treated mice to delineate the role of weight loss by CR as opposed to the role of GLP-1 agonism
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References Abbasi A, Corpeleijn E, Gansevoort RT, Gans ROB, Struck J, Schulte J, Hillege HL, van der Harst P, Stolk RP, Navis G, Bakker SJL (2014) Circulating peroxiredoxin 4 and type 2 diabetes risk: the prevention of renal and vascular endstage disease (PREVEND) study
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The compound was first characterized in metabolic research exploring the role of NNMT in adipose tissue biology
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