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Kidney function naturally declines with age, and GLP-1 medications are processed and eliminated through renal pathways, making baseline kidney assessment essential before treatment initiation in older adults

Am J Physiol Gastrointest Liver Physiol 2010;298:G364-G374

Reduced expression of the ferroptosis inhibitor glutathione peroxidase-4 in multiple sclerosis and experimental autoimmune encephalomyelitis

In vitro experiments have shown that liraglutide significantly reduces the proliferation of keratinocytes, inhibits the migration of macrophages to keratinocytes, and impairs the inflammatory reactions triggered by LPS in keratinocytes