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For some people cravings point to conditions such as diabetes thyroid dysfunction or a mood disorder

Consistent with the reductions in BRI, cardiovascular disease risk factors improved in Surmount 1, although sex differences could not be ascertained as male and female observations were pooled in the pivotal publication [2]

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This binding triggers several powerful effects: Slowing stomach emptying, making you feel fuller longer Reducing appetite signals in your brains hunger centre Improving insulin release and blood sugar control Blocking glucagon (a hormone that raises blood sugar) These medications work by mimicking the GLP-1 hormone, which is naturally produced by the gut after eating