While the results show great promise, significant challenges remain in reducing algorithmic bias across demographic groups, validating performance with diverse external datasets, prospective clinical evaluations, standardization of performance metrics, and clear regulatory pathways towards deployment (203, 204)
Additionally, [6]-shogaol and hydroxy -sanshool were found to be associated with an increase in ADM (adenylate cyclase-activating polypeptide) production
But Medicare coverage could have a bigger impact on who gets the drugs because the program covers about 66 million people, and is the primary source of insurance for people ages 65 and above
Gastrointestinal adverse events (nausea, diarrhea, constipation) were the most common side effects in Phase 2, consistent with the GLP-1 class
228 HernandezAFGreenJBJanmohamedSD'AgostinoRBGrangerCBJonesNPet al
J Clin Endocrinol Metab 99(7):24862493