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Consistent healthy lifestyle habits play an important role in maintaining optimal antioxidant defenses

Detailed experimental procedures are provided in Supporting Information

Persistent vomiting, severe abdominal pain, fainting, or signs of dehydration should be addressed quickly

Niacin also contributes to the synthesis of neurotransmitters, such as serotonin, a derivative of tryptophan, which is pivotal for mood regulation and various neurological functions, such as sleep and appetite, besides impacting cognitive and executive functions (13, 50)

Studies have found a correlation between low glutathione levels and insulin resistance, suggesting that enhancing glutathione levels may improve insulin sensitivity and support metabolic health

The ankles constant weight-bearing demands further complicate matters, as complete rest remains impractical for most people