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Supports lean muscle preservation during weight loss, improving body composition

A randomised placebo controlled exploratory study of vitamin B-12, lofepramine, and L-phenylalanine (the Cari Loder regime) in the treatment of multiple sclerosis

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A recent RCT involving 731 HFpEF patients with obesity found that tirzepatide reduced the risk of the composite outcome of cardiovascular death or worsening heart failure compared to placebo (HR 0.62