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Matthew Simone, FNP-BC is the founder of Homesteady Health and a board-certified Family Nurse Practitioner with more than 25 years across family medicine, emergency, and urgent care

Our testers reeled when trying it in plain water

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With 2 mL of water and a 1 mg daily dose (4 units), the vial lasts 50 days

In one study called TIPO-1, participants were given different doses of tesofensine or a placebo along with a reduced-calorie diet for 24 weeks

Both medicines are unlicensed in the UK, meaning they cannot be prescribed through standard NHS or private prescribing routes