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Ixekizumab is a humanized monoclonal antibody that blocks the actions of IL-17

drug desensitization therapy for specific allergens

Human CD4 + Th2 clones specific for the house dust mite allergen Der p I can be rendered non-responsive to subsequent Der p I challenges by incubating them with Der p I- derived peptides, representing the relevant minimal T-cell activation inducing epitopes, in the absence of professional APC (Yssel et al., 1994)

The risk appears dose-dependent, with lower research doses (20-40 mcg) showing minimal effects on blood glucose, while higher doses (80-100 mcg) may produce more pronounced effects on blood sugar levels