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As you can see from the side-by-side Figure below, the new trial (at left) replicates the previous one for symptomatic benefit and reduced physical limitations (Y-axis, corresponding to the Kansas City score) with the primary endpoint findings remarkably similar

However, imputed and complete-case analyses yielded results similar in direction and magnitude, confirming that our approach to handling missingness was suitable for the study

All patients receive physician oversight and remote monitoring included in this flat rate

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