ShahMARZhuFCuiYHuXChenHKayaniSIet al
16 The serum half-life of GSH after intravenous administration is less than 2 minutes
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Spiking blood simultaneously with extraction buffer (Sample Type 2) resulted in improved recoveries98% for NAD + , 85% for NADH (with only 10% converting to NAD + ), 95% for NADP + and 82% for NADPH
Clinical Relevance: These findings explain GHK-Cu's accelerated wound closure observed in clinical settings and its interest as a therapeutic candidate for chronic wounds, post-surgical recovery, and tissue regeneration applications
Safety Profile and Realistic Risk Assessment GHK-Cu demonstrates a generally favorable safety profile based on over 40 years of research, though most safety data derives from topical applications and animal studies