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These mitochondria are a primary source of ROS, making the kidneys especially susceptible to oxidative stress-related injury

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Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are approved for the treatment of type 2 diabetes and obesity

1g) that was suggestive of perturbed hepatic glutathione homeostasis

[114] randomized subjects to semaglutide or placebo to observe the change of liver fat from baseline to week 48, and found that semaglutide significantly reduced hepatic steatosis, improved liver enzymes and metabolic parameters, and had a positive effect on the diagnosis and treatment of NAFLD compared with placebo