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Lastly, beyond the absolute levels of BDNF and proBDNF, contemporary hypotheses emphasize the potential significance of the proBDNF/BDNF ratio

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Where patient-level incidence was available, the proportion with 1 AE ranged from 035% in treatment arms and 1046% in controls

We assessed the in vitro stability of Dox@vesicles by dispersion in PBS for 24 h, and as anticipated, there was no alteration in particle size during this period, as reported in Supplementary Fig

In clinical trials like SURMOUNT-1, approximately 6% to 7% of patients reported constipation, but in real-world clinical practice, we see this number much higher

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