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Our findings unexpectedly reveal that phosphorylation of just a small part of the Med14 protein plays a significant role in the response to GLP-1 drugs and in the metabolic response to hormones more broadly, added Reuben Shaw, a professor and holder of the William R

This evidence supports expanding access to semaglutide for cardiovascular protection beyond traditional weight-loss indications, potentially benefiting millions of patients with established cardiovascular disease regardless of their ability to lose weight on the medication

The autonomic nervous system (ANS) controls our body's automatic, unconscious functions, such as heart rate, blood pressure regulation, and digestion

Some patients may respond best to GLP-1 therapies alone, while others may see optimal results when combining medication with nutrition coaching, fitness guidance, or additional wellness services

says Dr Knuppel