glp-1 brain programs the neurovascular landscape: Cell Metabolism How GLP-1 Affects the Brain,

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10.1177/20587384211016194 122 MakhloughA.AlaS.Haj-HeydariZ.KashiZ.BariA

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20 Nrf2 and cancer risk Additionally, mutations in the Nrf2 gene in human studies have been associated with an increased risk of cancer, with the authors proposing that constance Nrf2 activity, prevents anti-cancer targeted oxidative stress, allowing cancer cells to survive

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Most mechanistic evidence derives from preclinical models, while human data remain largely associative