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But it stressed that dose-response relationships were not established and that there is insufficient clinical safety information to characterize BPC-157's human safety profile with no studies administering it to humans by the proposed routes

8 Further information is provided in three additional papers that reported data from the RAND Interstitial Cystitis Epidemiology (RICE) study

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this is expected and not harmful, but it can cause alarm or confusion if not anticipated

This is why many people notice a difference within days rather than weeks

158 Available findings have allowed us to speculate that the biological activities of oxidized AAT may depend on the magnitude of AAT oxidation, in a manner similar to that discussed for HSA (Figure 3)