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LEADER [29] and SUSTAIN-6 [30] reported a prespecified renal composite of new onset or persistent macroalbuminuria, persistent doubling of serum creatinine and eGFR 45 mL/min/1.73 m 2 , need for renal replacement therapy (RRT), and renal death
ALA is both water and fat-soluble, allowing it to work throughout the body, including the brain
8 , e1000450 (2010)
Cardiovascular Emerging Evidence Evidence Rating: Emerging (Preliminary animal data) Cardiovascular applications are less studied but intriguing: Cardiac protection Arrhythmia prevention Blood vessel healing Collateral vessel formation Regulatory Status FDA Classification BPC-157 is not approved by the FDA for any medical use in humans
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