With more severe injury, synapse disruption, axonal injury, excitotoxicity, and cell death also become major effectors
The process to license a drug can be very expensive, because it involves clinical trials
A 2023 meta-analysis of 11 randomized controlled trials found that GLP-1 monotherapy achieved average body weight reductions of 1222%, with improvements in blood glucose control, blood pressure, and cholesterol profiles as secondary benefits
It provides the essential electrolytes your body needs to maintain fluid balance, which is crucial for nutrient transport
However, that is not the reality: even diabetic patients treated with GLP-1 RAs are more likely to stop them than other second-line anti-diabetic medicines
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