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The above results show that GPX4 is upregulated by anticancer therapies in vivo, and GPX4 inhibitors in combination with cisplatin reduced tumour size and increased survival in a mouse model of ovarian cancer

H tr qu trnh kh c: Kt hp vi cc enzym nh glutathione S-transferase gip chuyn i cc cht c kh tan thnh dng d ha tan v c thi tr qua nc tiu hoc mt

The following are prohibited: M2.1

Myeloproliferative disorders

The washout allows receptor resensitization while newly formed mitochondria continue operating at baseline

The compound has not progressed through standard pharmaceutical-development trials for any therapeutic indication