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A study published in BMC Complementary and Alternative Medicine (Son et al., 2015) found that [6]-gingerol significantly elevated plasma GLP-1 levels in diabetic mice and upregulated the pathways that control insulin granule release in pancreatic beta cells
So far, oral GLP-1 therapies have been developed to reduce patient reliance on injections
As a male fertility specialist, I view these findings as highly encouraging, Werthman emphasized
In addition, some aspects of GLP-1 beyond weight loss, such as preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, still deserve a greater insight, especially in light of a possible therapeutic use in PCOS women independently of obesity
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