IgG is an aging factor that drives adipose tissue fibrosis and metabolic decline
Program of Shanghai Academic/Technology Research Leader (23XD1400900 to D.Y.) and Shanghai Sailing Program (22YF1457200 to F.Z.)
The activity half-life in rat of exendin-4 in fusion with a carrier antibody has been previously reported as 10.8 h 26 , which is similar to the 11.5 h value we observed in mice for exendin-4 in fusion with the anti-PCSK9 Ab#2 antibody (Supplementary Table 4)
For full results, especially in fat loss, it may take several months of consistent use
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