This deficiency can lead to a wide array of severe health problems (Figure 2), including megaloblastic anemia and irreversible neurological damage (13)
PubMed , Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline , National Academies Press (US), 1998
A Phase I oral safety trial has been completed [9] , and a small human case series reported improvements following intra-articular administration [5]
References [i] Philp, D., Hernanadez, G., Kleinman, H
The cholesteryl ester cycle in macrophage foam cells
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