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Its clinical program in the late 2000s was built around large, rigorously controlled trials with a hard imaging endpoint (visceral adipose tissue measured by CT), and it culminated in FDA approval in 2010

Annual Review of Pathology

Unfortunately, the small sample size and the lack of thyroid function data of enrolled patients prevent drawing conclusions on this possible effect

F., and Burgard, P

97 Moreover, ceruloplasmin is a physiologic inhibitor of MPO, 98 a neutrophil enzyme that promotes oxidative stress in COPD

In August 2023, avacincaptad pegol was approved for treating geographic atrophy (GA) secondary to dry AMD