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The timeline can look a little different for each person, especially for women whose hormones, age, and metabolism all influence how quickly changes show up

Because tirzepatide engages an additional receptor pathway, some patients report slightly more pronounced gastrointestinal effects initially, though this typically resolves within 46 weeks

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For people with type 2 diabetes, Ozempic helps regulate blood sugar levels by stimulating insulin secretion when glucose levels are elevated and suppressing glucagon release

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Keeping detailed notes about how you feel during the first week helps your healthcare provider optimize your treatment plan at subsequent dose increases