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Vomiting nearly doubles

Heartburn was not consistently reported as a standalone symptom in trials, but overlapping symptoms suggest reflux-type discomfort is plausible

First, findings across studies may vary due to differences in surgical techniques, such as Roux-en-Y gastric bypass versus sleeve gastrectomy, which elicit distinct hormonal responses

The dosing should always be determined by your doctor

PRISMA 2020 Checklist Figure & Data References Citations Citations to this article as recorded by The efficacy and safety of dual GIP/GLP1 receptor agonists (tirzepatide) in diabetes and obesity: a systematic review and network meta-analysis Karolina Hoffmann, Micha Michalak, Manfredi Rizzo, Viviana Maggio, Anna Paczkowska Expert Opinion on Drug Safety.2026