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So, PIONEER 2, 48 measured patient-reported outcomes better understand the patient satisfaction with oral semaglutide and the impact of the treatment on well-being, quality of life, and weight-related quality of life compared with other active standard-of-care medications [40, 42, 43, 45, 46]
People with diabetes who take Semaglutide have about the same rate of side effects as people who don't have diabetes
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The GIP component appears to blunt GLP-1-associated nausea, which is one reason discontinuation rates for tirzepatide are lower than for pure GLP-1 agonists at equivalent weight-loss doses [1]
Beyond the scientific claims, its marketing schtick is all about soft, understated opulence because, y'know, quiet luxury is gospel
