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The rationale for combining them is mechanistic complementarity

This may also depend on your diet, how many prebiotic foods you consume, and other probiotic foods in your diet as well

Here's how Midi's medical experts think about the specific concerns that tend to drive interest in ipamorelin: If you want to support growth hormone levels: Ask a clinician about sermorelin, a prescription medication that works similarly to ipamorelinbut with decades of safety data and far cleaner clinical evidence behind it

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J Biomed Mater Res B Appl Biomater (2022) 110(8):1796805

It's based on the natural peptide tuftsin