is supported by US National Institutes of Health (NIH) grants R01-DK55758, P01-DK088761, R01-DK099110 and P01-AG051459 and by an unrestricted grant from the Novo Nordisk Research Foundation
The median overall survival (OS) was 24.5 months for Pluvicto-treated patients, compared to 23.1 months for those receiving ARPIs alone
however, individuals already taking glucose-lowering medicines (including insulin) may be at increased risk of hypoglycaemia if GH-mediated effects alter their insulin sensitivity Injection site reactions, including pain, redness, and infection risk For retatrutide , the side effect profile observed in clinical trials is consistent with that of other GLP-1 receptor agonists and includes nausea, vomiting, diarrhoea, and constipation
Sifuentes-Franco S, Snchez-Macas DC, Carrillo-Ibarra S, Rivera-Valds JJ, Zuiga LY, Snchez-Lpez VA
doi: 10.1038/s42255-024-01113-9 2 DruckerDJ
So that's a concern