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During the four-year follow-up period, 7 out of 113 individuals on the placebo developed primary liver cancer, while none of the 113 subjects supplemented with selenium developed liver cancer (80)

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Hyperandrogenism and oxidative stress in the ovaries triggers NLRP3 inflammasome-activated caspase-1 dependent pyroptosis, and eventually leading to the production of interleukin (IL)-1 and IL-18 [33]

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