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N Engl J Med 2008;359:1577-89

Providers consider factors such as medical history, weight loss goals, side effect tolerance, and overall metabolic health before recommending treatment

Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion

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The importance of antioxidant GPX4 and ROS signaling in necroptosis of erythrocyte precursors has been attributed to an oxidative environment linked to the accumulation of hemoglobin [156]