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Achtyes E, Keaton SA, Smart LA, Burmeister AR, Heilman PL, Krzyzanowski S, et al

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10.1523/jneurosci.15-03-01835.1995 J

The TRPV4 antagonist GSK2193874, as a preventive treatment, inhibits NMDAR-mediated excitotoxicity and NLRP3 inflammasome activation, and reduces the seizure rate [194]