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Human islet isolation and culture Human islet studies were approved by the National Research Ethics Committee London (REC 07/H0711/114)

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From 4 to 16 wk of age, mice were treated with the addition of 14.193 g sodium citrate and 12.872 g citric acid per litre to the drinking water, along with standard mouse feed pellets

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Triggering oxidative stress , producing free radicals that inflame tissues