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Refrigeration doesn't stop degradation entirely, but it slows it down to a crawl, preserving the peptide's integrity for the typical duration of a research protocol (usually 30-60 days post-reconstitution)

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This concept highlights the intricate, bidirectional communication among the gastrointestinal tract, the central nervous system (CNS), and the kidneys where dysfunction in one system can lead to cascading effects on the others (Yang et al., 2018)

One of the most important conditions to judge a CNS drug is to figure out whether it has BBB permeability or not

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