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In summary, viral persistence could play a major role in PASC, considering the ability of the SARS-CoV-2 pathogen to infect and reinfect individuals over a lifetime 274

By inhibiting the NF-B pathway and competitively antagonizing pro-inflammatory metabolites of arachidonic acid (such as PGE and LTB), they exert anti-inflammatory and cartilage-protective effects (39, 40)