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Source : Haq, I., Imran, M., Nadeem, M., Tufail, T., Gondal, TA, Mubarak, MS (2020)

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These cells release the peptides growth hormone-releasing hormone (GHRH or somatocrinin ) and growth hormone-inhibiting hormone (GHIH or somatostatin ) into the hypophyseal portal venous blood surrounding the pituitary

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From this research it seems that the best explanations may be through the potential reset of a disrupted methionine-folate cycle and aiding in the removal of toxic metals and chemicals from the brain