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Lipoic acid was found to effectively slow disease progression when administered either orally (87), intraperitoneally (88), or subcutaneously (89) to mice with experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis

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As a final step, depending on the nature of the activation signal, FOXO can regulate apoptosis[257], cell cycle[258], differentiation[256], or the expression of genes involved in DNA repair[259] and oxidative stress resistance[260]

The outcome of this in mice was incredible