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Any extra that isnt immediately required isnt stored long term, unlike fatsoluble vitamins (A, D, E, and K)
Since we do not expect that TAT-DAT NT would have opposite effects at different doses, we did not perform in vivo microdialysis for different doses of TAT-DAT NT
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This pattern aligns with B12 pharmacokinetics: serum levels peak 8-12 hours post-injection, tissue saturation occurs over 48-72 hours (Andrs et al., Journal of Blood Medicine , 2018)
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