glp 1 beta cell regeneration JCI Insight Molecular mechanisms redirecting the GLP-1

Callaway Jr

The ORIGIN trial showed that insulin glargine neither increased nor decreased cardiovascular events compared to standard care

Our approach: Start low, go slow: Begin with the lowest effective dose Titrate every 4 weeks, only if tolerated Monitor for side effects at every visit Evaluate efficacy at 36 months For population health leaders, thoughtful prescribing: -Reduces complications from uncontrolled metabolic conditions -Lowers medication waste -Drives down long-term healthcare spend When used with intention, GLP-1s and, most importantly, coming off of them after building metabolic resilience, can help people reclaim agency over their health long-term

J Nat Prod 1998

Lizarrondo, J

The app assigns users a color-coded food system and connects them with human coaches