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The semaglutide group were significantly less likely to experience MACE

Nutr Metab

Cortisol, Stress, and Appetite Regulation One underappreciated hormonal interaction involves cortisol

Patients were included if they had baseline bilateral pain radiographs demonstrating Kellgren and Lawrence grades of 1 to 3, as well as at least 2 years of follow-up before the initiation of GLP-1RA therapy for the sake of comparisons between groups

Despite the limitations of real-world observational studiesincluding the absence of randomization, control for confounding variables, and inability to establish causalityresearches offer confidence regarding the pancreatic safety profiles of GLP-1 RAs [55,61]

References Berg AH, Scherer PE