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Beyond its potential GLP-1 effects, curcumin offers broad anti-inflammatory benefits that may support overall metabolic health

The total amount lost and the speed of loss also mattersomeone who loses 50+ pounds in a year will likely see more skin changes than someone who loses 20

Varying genetic makeups, microbiomes, metabolic rates, starting BMIs all account for discrepancies amongst patients

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S-nitrosylation involves the covalent attachment of a NO group to cysteine thiols, specifically Cys94 and Cys99 of eNOS, forming S-nitrosothiols (SNOs) (Erwin et al., 2006)