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Conclusions Recent advances in this field have highlighted the importance of GST activities and the role that these enzymes play in diverse cellular processes as well as in conferring resistance to chemotherapy

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Space sessions 12 weeks apart for an initial series, transitioning to monthly maintenance once results are established

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Its pathophysiology involves multiple interconnected mechanisms, including monoaminergic neurotransmitter depletion, impaired neurotrophic signaling, neuroinflammation accompanied by hypothalamic-pituitary-adrenal (HPA) axis dysregulation, and glutamate-induced excitotoxicity (Medeir et al., 2020)