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This article was financially supported by National Institutes of Health Public Health Service grants R01 HL144790, R01 HL151493, R01 AI145813, R01 AI169687, R01 HL151769, and R01 HL159804 (OA)

Participants in both groups received individual counselling sessions to help them adhere to a reduced-calorie diet (500-kcal deficit per day relative to the estimated energy expenditure at the time) and increased physical activity (150 min per week of activities such as walking)

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It can also slow results, so it is a tradeoff to discuss

Both types reduce stomach acid by about 20.7% [2]