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95% CI 1.05 to 1.44), with longer treatment periods associated with a greater risk [90]

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Within the hypothalamus, GLP-1 interacts with pro-opiomelanocortin (POMC) neurons in the arcuate nucleus (it seems to have limited direct access here), a classic site involved in appetite regulation and energy expenditure

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51.Wadden T.A., Brown G.K., Egebjerg C., Frenkel O., Goldman B., Kushner R.F., McGowan B., Overvad M., Fink-Jensen A