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Recent mechanistic and epidemiological evidence indicates that conditions such as obesity, type 2 diabetes mellitus, hypertriglyceridemia, coronary heart disease, coronary slow-flow phenomenon, and diabetic peripheral neuropathy share common pathophysiological pathways, most notably insulin resistance, chronic inflammation, lipid metabolism disturbances, and endothelial dysfunction

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Glutathione: overview of its protective roles, measurement, and biosynthesis

A Promising Future for Glutathione in Longevity Research GSHs ability to enhance detoxification and target multiple hallmarks of aging, such as oxidative stress and mitochondrial dysfunction, positions it as a top candidate for longevity interventions

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We demonstrated that 1 of the chemical chaperones (corr-4a) reduced the degradation of cystinosin(7) and facilitated its trafficking to the lysosome