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However, implementation of eryptosis assays in nanotoxicology can be limited by the lack of a generally accepted single eryptosis marker and the requirements to use several markers simultaneously, their lower cost-effectiveness compared to the hemolysis assays, and the availability of the equipment, since eryptosis detection is primarily flow cytometry-based

Front Physiol 2018;9:419

The biomarker changes were shown to correspond with endpoints such as improved gait and body composition

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