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Description

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Antidepressants , including low doses of tricyclic antidepressants or SSRIs, to manage pain and other symptoms through effects on the gut-brain axis

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Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized

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For drugs with short half-lives, poor compliance with prescribed treatment regimens reduces plasma concentrations to unsuitable levels, and multiple doses are often required to return to therapeutic plasma concentrations

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The specific drug names can be found in Supplemental Table 3

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