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29 The addition of D5W to fluids also prevents hypoglycemia by serving as an exogenous source of glucose in the setting of insulin utilization

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These mechanisms lead to the prolonged activation of trigeminal neurons, astrocytes, and microglia around meningeal blood vessels, inflammatory cascades within brain parenchyma reaching the glia limitans, and the dispersal of arachidonic acid (AA) and potassium ions into the perivascular area (9, 10, 39)

Anecdotes are interesting, but data is king