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Data show that up to two-thirds of patients with HFpEF have CAD or coronary microvascular dysfunction including ischaemia, which leads to disruption of LV diastolic and systolic function, development of fibrosis, increased myocardial stiffness and cardiac remodelling

Access and reimbursement will also vary, shaped by each countrys health policies and ongoing reviews of cost-effectiveness for obesity treatments

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The nutritional strategy for GLP-1 therapy must go hand in hand with the medication, including proper injection technique and picking the right place to inject

Yet, stopping Wegovy often brings concerns about hunger returning and the potential for weight rebound

2003 Dec;31(12):1499-506