4 Discussion Considering the clinical utility of low serum GPX-3 concentration (or GPX-3 deficiency) in various diseases, in this study we investigated whether serum GPX-3 concentration at diagnosis could be used to assess vasculitis activity and damage at diagnosis in immunosuppressive drug-naive patients with AAV, and obtained some interesting findings
Ethical considerations: equity of access to life-extension therapies, off-label usage, anti-ageing claims and regulatory scrutiny
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Structures of the GLP-1R in complex with G s , bound with GLP-1 and exendin-P5, as well as non-peptide ligands, have been determined using cryo-EM 13, 16, 27
101.3 Measuring What Matters in Primary Care: Health-Related Quality of Life and Its Predictors Among Users of Public Primary Care Clinics in Singapore Using the EQ-5D-5L Ling Jie Cheng 1 , Qin Xiang Ng 2 , Guang Jie Justin Lee 2 , Gerald Choon Huat Koh 3 , Nan Luo 3 1 National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK, 2 Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore, 3 Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :101.3 Aims Health-related quality of life (HRQoL) is increasingly recognised as a key outcome in healthcare delivery, particularly in primary care settings where multimorbidity is rising
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