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Phase 2a clinical testing of a first-in-class small-molecule compound that targets a p75 neurotrophin receptor, for example, demonstrated potential efficacy in slowing AD pathology in participants with mild to moderate AD, as measured by CSF biomarkers amyloid beta40 and amyloid beta42

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The approval is based on breakthrough evidence from the landmark EMPA-REG OUTCOME trial, which investigated the effects of JARDIANCE compared with placebo when added to standard of care type 2 diabetes and cardiovascular medicines in adults with type 2 diabetes and established cardiovascular disease

Start your intake Understanding GLP-1 Medications and Ulcerative Colitis Risk GLP-1 receptor agonists slow stomach emptying and reduce appetite by mimicking glucagon-like peptide-1, a natural hormone your body produces